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KMID : 0364219750180030147
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Korean Journal of Zoology
1975 Volume.18 No. 3 p.147 ~ p.156
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Effect of Low Atmospheric Pressure on Serum Glutamic Oxaloacetic Transaminase and Lactic Dehydrogenase Activities of Rats
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Masancay Teresita E.
Nam Sang-Yul
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Abstract
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In order to determine the influence of low atmospheric pressure on serum glutamic oxaloacetic transaminase (SGOT) and serum lactic dehydrogenase (SLDH) activities of rats, blood samples were collected from laboratory-conditioned male rats of the Sprague-Dawley strain which were randomly grouped into control and the experimental subjected to a series of one hour-exposure a day to low atmospheric pressure of 500 and 380mmHg up to the the time of 15 day. Results obtained indicated that decompression caused marked alterations in SGOT and SLDH levels when compared to that of the control. The trend of increases or decreases in these enzyme levels were similar in both 500 and 380mmHg exposed rats although the changes were greater in the latter group. Thus, generally all the experimental rats showed temporary steady state to low atmospheric pressure. Changes in enzymatic contents depended on the intensity and extent of the environmental stress under study. The lower the atmospheric pressure the greater is the effect on these serum enzyme levels.
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KEYWORD
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